Guinea is approximately 245,857 sq km, while American Samoa is approximately 224 sq km, making American Samoa 0.09% the size of Guinea. Meanwhile, the population of Guinea is ~12.5 million people (12.5 million fewer people live in American Samoa).
This to-scale map shows a size comparison of Guinea compared to American Samoa. For more details, see an in-depth quality of life comparison of American Samoa vs. Guinea using our country comparison tool.