Alaska is about 1,537 times bigger than Sao Tome and Principe.

Sao Tome and Principe is approximately 964 sq km, while Alaska is approximately 1,481,348 sq km, making Alaska 153,567% larger than Sao Tome and Principe. Meanwhile, the population of Sao Tome and Principe is ~217,164 people (493,067 more people live in Alaska).
Tip: This to-scale comparison of Sao Tome and Principe vs. Alaska uses the Mercator projection, which distorts the size of regions near the poles.