Alaska is about 20 times bigger than Panama.

Panama is approximately 75,420 sq km, while Alaska is approximately 1,481,348 sq km, making Alaska 1,864% larger than Panama. Meanwhile, the population of Panama is ~4.3 million people (3.6 million fewer people live in Alaska).
Tip: This to-scale comparison of Panama vs. Alaska uses the Mercator projection, which distorts the size of regions near the poles.