San Francisco is around the same size as South Bend.

South Bend (map shows its 30 named neighbourhoods; the area covers the whole city) is approximately 109 sq km, while San Francisco (including the city proper only) is approximately 121 sq km, making San Francisco 12% larger than South Bend.
Tip: This to-scale comparison of South Bend vs. San Francisco uses the Mercator projection, which distorts the size of regions near the poles.
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