San Francisco is about 1.6 times smaller than Potsdam.

Potsdam is approximately 188 sq km, while San Francisco (including the city proper only) is approximately 121 sq km, making San Francisco 64.27% the size of Potsdam.
Tip: This to-scale comparison of Potsdam vs. San Francisco uses the Mercator projection, which distorts the size of regions near the poles.
Our free app, MapSize by MyLifeElsewhere — compare any two places, to scale on your mobile device.