Prague is about 3 times smaller than Mexico City.

Mexico City is approximately 1,485 sq km, while Prague is approximately 496 sq km, making Prague 33.41% the size of Mexico City.
Tip: This to-scale comparison of Mexico City vs. Prague uses the Mercator projection, which distorts the size of regions near the poles.
Our free app, MapSize by MyLifeElsewhere — compare any two places, to scale on your mobile device.