New York City is about 2.6 times smaller than Santiago.

Santiago (area of the 32 comunas of Santiago Province) is approximately 2,030 sq km, while New York City (including all five boroughs: Manhattan, Brooklyn, Queens, The Bronx, and Staten Island) is approximately 781 sq km, making New York City 38.47% the size of Santiago.
Tip: This to-scale comparison of Santiago vs. New York City uses the Mercator projection, which distorts the size of regions near the poles.
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