Manchester is about 46 times smaller than Istanbul.

Istanbul is approximately 5,343 sq km, while Manchester is approximately 116 sq km, making Manchester 2.16% the size of Istanbul.
Tip: This to-scale comparison of Istanbul vs. Manchester uses the Mercator projection, which distorts the size of regions near the poles.
Our free app, MapSize by MyLifeElsewhere — compare any two places, to scale on your mobile device.