Los Angeles is about 39 times bigger than San Mateo.

San Mateo is approximately 31 sq km, while Los Angeles (including the city proper only) is approximately 1,215 sq km, making Los Angeles 3,765% larger than San Mateo.
Tip: This to-scale comparison of San Mateo vs. Los Angeles uses the Mercator projection, which distorts the size of regions near the poles.
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