Los Angeles is about 6 times bigger than Madison.

Madison (map shows its 124 named neighbourhoods; the area covers the whole city) is approximately 217 sq km, while Los Angeles (including the city proper only) is approximately 1,215 sq km, making Los Angeles 461% larger than Madison.
Tip: This to-scale comparison of Madison vs. Los Angeles uses the Mercator projection, which distorts the size of regions near the poles.
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