Indianapolis is about 17 times bigger than Portland.

Portland (map shows its 17 named neighbourhoods; the area covers the whole city) is approximately 56 sq km, while Indianapolis is approximately 935 sq km, making Indianapolis 1,576% larger than Portland.
Tip: This to-scale comparison of Portland vs. Indianapolis uses the Mercator projection, which distorts the size of regions near the poles.
Our free app, MapSize by MyLifeElsewhere — compare any two places, to scale on your mobile device.