Indianapolis is about 2.1 times smaller than Jacksonville.

Jacksonville (map shows its 197 named neighbourhoods; the area covers the whole city) is approximately 1,935 sq km, while Indianapolis is approximately 935 sq km, making Indianapolis 48.31% the size of Jacksonville.
Tip: This to-scale comparison of Jacksonville vs. Indianapolis uses the Mercator projection, which distorts the size of regions near the poles.
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