Indianapolis is about 2.5 times bigger than Birmingham.

Birmingham (map shows its 87 named neighbourhoods; the area covers the whole city) is approximately 381 sq km, while Indianapolis is approximately 935 sq km, making Indianapolis 145% larger than Birmingham.
Tip: This to-scale comparison of Birmingham vs. Indianapolis uses the Mercator projection, which distorts the size of regions near the poles.
Our free app, MapSize by MyLifeElsewhere — compare any two places, to scale on your mobile device.